Toxicity

/Toxicity

Colchicine Ventricular extrasystoles

By | 2016-11-29T03:01:31+00:00 November 22nd, 2016|Cardiac Toxicity|

Drug / Chemical name: Colchicine Adverse Effect / Toxicity: Ventricular extrasystoles Species: Human Dose: 53x500 ug/24-48 h Dose type: Repeated Route: Oral M.J. Maxwell, P. Muthu, P.E. Pritty, Accidental colchicine overdose. A case report and literature review, Emerg Med J. 19 (2002) 265–266. doi:10.1136/emj.19.3.265. [...]

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Phenylephrine Hydrochloride Arrhythmia

By | 2016-11-29T03:01:31+00:00 November 22nd, 2016|Cardiac Toxicity|

Drug / Chemical name: Phenylephrine Hydrochloride Adverse Effect / Toxicity: Arrhythmia Species: Human Dose: 20 mg Dose type: Single Route: Ocular Y.K. Lai, Adverse effect of intraoperative phenylephrine 10%: case report., Br J Ophthalmol. 73 (1989) 468–469. doi:10.1136/bjo.73.6.468.3.

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Phenylephrine Hydrochloride Myocardial infarction

By | 2016-11-29T03:01:31+00:00 November 22nd, 2016|Cardiac Toxicity|

Drug / Chemical name: Phenylephrine Hydrochloride Adverse Effect / Toxicity: Myocardial infarction Species: Human Dose: 20 mg Dose type: Single Route: Ocular Y.K. Lai, Adverse effect of intraoperative phenylephrine 10%: case report., Br J Ophthalmol. 73 (1989) 468–469. doi:10.1136/bjo.73.6.468.3.

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Levobunolol Hydrochloride

By | 2016-11-29T03:01:31+00:00 November 22nd, 2016|Cardiac Toxicity|

Drug / Chemical name: Levobunolol Hydrochloride Adverse Effect / Toxicity: Sinus bradycardia Species: Human Dose: 0.5%/1Y Dose type: Repeated Route: Ocular M. Ober, A. Scharrer, R. David, B.Z. Biedner, G.D. Novack, J.C. Lue, D.S. Robins, E. Duzman, Long-term ocular hypotensive effect of levobunolol: results of a one-year [...]

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Abatacept Myocardial infarction

By | 2016-11-29T03:01:31+00:00 November 22nd, 2016|Cardiac Toxicity|

Drug / Chemical name: Abatacept Adverse Effect / Toxicity: Myocardial infarction Species: Human Dose: 10 mg/kg/1, 15 and 29D, and every 4W thereafter up to and including day 141 Dose type: Repeated Route: Intravenous M. Schiff, C. Pritchard, J.E. Huffstutter, V. Rodriguez-Valverde, P. Durez, X. Zhou, T. [...]

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Abatacept Cardiac arrest

By | 2016-11-29T03:01:32+00:00 November 22nd, 2016|Cardiac Toxicity|

Drug / Chemical name: Abatacept Adverse Effect / Toxicity: Cardiac arrest Species: Human Dose: 10 mg/kg/1, 15 and 29D, and every 4W thereafter up to and including day 141 Dose type: Repeated Route: Intravenous M. Schiff, C. Pritchard, J.E. Huffstutter, V. Rodriguez-Valverde, P. Durez, X. Zhou, T. [...]

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Abatacept Cardiac failure congestive

By | 2016-11-29T03:01:32+00:00 November 22nd, 2016|Cardiac Toxicity|

Drug / Chemical name: Abatacept Adverse Effect / Toxicity: Cardiac failure congestive Species: Human Dose: 10 mg/kg/1, 15 and 29D, and every 4W thereafter up to and including day 141 Dose type: Repeated Route: Intravenous M. Schiff, C. Pritchard, J.E. Huffstutter, V. Rodriguez-Valverde, P. Durez, X. Zhou, [...]

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Adalimumab Myocardial infarction-1

By | 2016-11-29T03:01:32+00:00 November 22nd, 2016|Cardiac Toxicity|

Drug / Chemical name: Adalimumab Adverse Effect / Toxicity: Myocardial infarction Species: Human Dose: 20 mg/every other week Dose type: Repeated Route: Subcutaneous L.B.A. van de Putte, C. Atkins, M. Malaise, J. Sany, A.S. Russell, P.L.C.M. van Riel, L. Settas, J.W. Bijlsma, S. Todesco, M. Dougados, P. [...]

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Adalimumab Myocardial infarction

By | 2016-11-29T03:01:32+00:00 November 22nd, 2016|Cardiac Toxicity|

Drug / Chemical name: Adalimumab Adverse Effect / Toxicity: Myocardial infarction Species: Human Dose: 80 mg/12W Dose type: Repeated Route: Subcutaneous [1] L.B.A. van de Putte, R. Rau, F.C. Breedveld, J.R. Kalden, M.G. Malaise, P.L.C.M. van Riel, M. Schattenkirchner, P. Emery, G.R. Burmester, H. Zeidler, H.M. Moutsopoulos, [...]

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Dexamethasone

By | 2016-11-29T03:01:32+00:00 November 22nd, 2016|Cardiac Toxicity|

Drug / Chemical name: Dexamethasone Adverse Effect / Toxicity: Bradycardia Species: Human Dose: 0.15 mg/kg/90D Dose type: Repeated Route: Unknown P.C. Ng, K.G. Brownlee, P.R. Dear, Gastroduodenal perforation in preterm babies treated with dexamethasone for bronchopulmonary dysplasia., Arch Dis Child. 66 (1991) 1164–1166. doi:10.1136/adc.66.10_Spec_No.1164. [...]

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