Drug / Chemical name: Tocainide Hydrochloride Adverse Effect / Toxicity: Sinus bradycardia Species: Human Dose: 1200 mg Dose type: Repeated Route: Oral S.K. Mandal, S.K. Datta, Nodal bradycardia induced by tocainide., Postgrad Med J. 59 (1983) 262–263. doi:10.1136/pgmj.59.690.262.
Drug / Chemical name: Sotalol Hydrochloride Adverse Effect / Toxicity: Torsade de pointes Species: Human Dose: 640 mg/day Dose type: Repeated Route: Oral A. Kontopoulos, F. Manoudis, A. Filindris, P. Metaxas, Sotalol-induced torsade de pointes, Postgrad Med J. 57 (1981) 321–323. doi:10.1136/pgmj.57.667.321.
Drug / Chemical name: Sotalol Hydrochloride Adverse Effect / Toxicity: Bradycardia Species: Human Dose: 640 mg/day Dose type: Repeated Route: Oral A. Kontopoulos, F. Manoudis, A. Filindris, P. Metaxas, Sotalol-induced torsade de pointes, Postgrad Med J. 57 (1981) 321–323. doi:10.1136/pgmj.57.667.321.
Drug / Chemical name: Mianserin Adverse Effect / Toxicity: Left ventricular dysfunction Species: Human Dose: 60 mg Dose type: Repeated Route: Oral C.D. Burgess, S. Montgomery, J. Wadsworth, P. Turner, Cardiovascular effects of amitriptyline, mianserin, zimelidine and nomifensine in depressed patients., Postgrad Med J. 55 (1979) 704–708. [...]
Drug / Chemical name: Amitriptyline Hydrochloride Adverse Effect / Toxicity: Tachycardia Species: Human Dose: 150 mg Dose type: Repeated Route: Oral C.D. Burgess, S. Montgomery, J. Wadsworth, P. Turner, Cardiovascular effects of amitriptyline, mianserin, zimelidine and nomifensine in depressed patients., Postgrad Med J. 55 (1979) 704–708. doi:10.1136/pgmj.55.648.704. [...]
Drug / Chemical name: Carteolol Hydrochloride Adverse Effect / Toxicity: Bradycardia Species: Human Dose: 2%/60D Dose type: Repeated Route: Ocular P. Demailly, C. Allaire, C. Trinquand, Ocular hypotensive efficacy and safety of once daily carteolol alginate, Br J Ophthalmol. 85 (2001) 921–924. doi:10.1136/bjo.85.8.921.
Drug / Chemical name: Phenindione Adverse Effect / Toxicity: Tachycardia Species: Human Dose: 150 mg/4W Dose type: Repeated Route: Oral J.S. Wright, Phenindione sensitivity with leukaemoid reaction and hepato-renal damage., Postgraduate Medical Journal. 46 (1970) 452.
Drug / Chemical name: Lofepramine Adverse Effect / Toxicity: Palpitations Species: Human Dose: 70 mg/day/24W Dose type: Repeated Route: Oral D.T. Wade, C.A. Young, K.R. Chaudhuri, D.L.W. Davidson, A randomised placebo controlled exploratory study of vitamin B-12, lofepramine, and L-phenylalanine (the “Cari Loder regime”) in the treatment [...]
Drug / Chemical name: Ipecac Syrup Adverse Effect / Toxicity: Cardiomyopathy Species: Human Dose: Several 30 mL doses/week/6M Dose type: Repeated Route: Oral L.P. Dresser, E.W. Massey, E.E. Johnson, E. Bossen, Ipecac myopathy and cardiomyopathy., J Neurol Neurosurg Psychiatry. 56 (1993) 560–562. doi:10.1136/jnnp.56.5.560.
Drug / Chemical name: Mesulergine Adverse Effect / Toxicity: Bundle branch block right Species: Human Dose: 0.1 mg/21.9 months Dose type: Repeated Route: Oral A. Wright, A.J. Lees, G.M. Stern, Mesulergine and pergolide in previously untreated Parkinson’s disease., J Neurol Neurosurg Psychiatry. 50 (1987) 482–484. doi:10.1136/jnnp.50.4.482. [...]
