Drug / Chemical name: Abatacept Adverse Effect / Toxicity: Cardiovascular disorder Species: Human Dose: 10 mg/kg/12 months Dose type: Repeated Route: Intravenous Storage, S. S., Agrawal, H. & Furst, D. E. Description of the Efficacy and Safety of Three New Biologics in the Treatment of Rheumatoid Arthritis. [...]
We are preparing the GSI-ToxDB web site. As soon as possible, we will release the web based Toxicity DB service. This database will include cardiac toxicity, hepatotoxicity and nephrotoxicity data.
Drug / Chemical name: Metaxalone Adverse Effect / Toxicity: Tachycardia Species: Human Dose: 2400 mg Dose type: Single Route: Oral Forrester, M. B. Adult metaxalone ingestions reported to Texas poison control centers, 2000-2006. Human & Experimental Toxicology 29, 55–62 (2010).
Drug / Chemical name: Efalizumab Adverse Effect / Toxicity: Cardiopulmonary failure Species: Human Dose: 1.0 mg/kg/weekly, 11W Dose type: Repeated Route: Subcutaneous Lotti, T. et al. Efficacy and Safety of Efalizumab in Patients with Moderate-to-Severe Plaque Psoriasis Resistant to Previous Anti-Psoriatic Treatment: Results of a Multicentre, Open-label, Phase IIIb/IV [...]